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SLC9A3R1 Rabbit pAb

Anti-SLC9A3R1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221784

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221784
Product Name:   Anti-SLC9A3R1 Rabbit Polyclonal Antibody
Synonyms:   EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
UNIPROT ID:   O14745 (Gene Accession – NP_004243 )
Background:    This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.
Immunogen:    Synthetic peptide of human SLC9A3R1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 500-1000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 221784(SLC9A3R1 Antibody) at a dilution of 1/25(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 221784(Anti-SLC9A3R1 Antibody) at dilution 1/25.
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