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DMGDH Rabbit pAb

Anti-DMGDH Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221911

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221911
Product Name:   Anti-DMGDH Rabbit Polyclonal Antibody
Synonyms:   DMGDHD; ME2GLYDH
UNIPROT ID:   Q9UI17 (Gene Accession – NP_037523 )
Background:    This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matri,x and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human DMGDH
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 221911(DMGDH Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 221911(Anti-DMGDH Antibody) at dilution 1/30.
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