Email: info@neweastbio.com   |  Call: 6109452007

DNAJB4 Rabbit pAb

Anti-DNAJB4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221914

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221914
Product Name:   Anti-DNAJB4 Rabbit Polyclonal Antibody
Synonyms:   DjB4; HLJ1; DNAJW
UNIPROT ID:   Q9UDY4 (Gene Accession – NP_008965 )
Background:    The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human DNAJB4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221914(DNAJB4 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221914(Anti-DNAJB4 Antibody) at dilution 1/20.
          Publications