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ELL2 Rabbit pAb

Anti-ELL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221943

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221943
Product Name:   Anti-ELL2 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   O00472 (Gene Accession – NP_036213 )
Background:    ELL2 (RNA polymerase II elongation factor ELL2) is a 640 amino acid nuclear protein that belongs to the ELL/occludin family. This family is defined by a highly conserved domain of approximately 100 amino residues found within all eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. These elongation factors activate elongation by suppressing transient pausing by polymerase at many sites along the DNA and govern its interaction with RNA polymerase II and the ternary elongation complex. ELL2 may also contain a novel type of RNA polymerase II interaction domain that is capable of negatively regulating polymerase activity in promoter-specific transcription initiation in vitro.
Immunogen:    Synthetic peptide of human ELL2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221943(ELL2 Antibody) at a dilution of 1/30(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221943(Anti-ELL2 Antibody) at dilution 1/30.
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