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EXD2 Rabbit pAb

Anti-EXD2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221992

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221992
Product Name:   Anti-EXD2 Rabbit Polyclonal Antibody
Synonyms:   EXDL2; C14orf114
UNIPROT ID:   Q9NVH0 (Gene Accession – NP_001180291 )
Background:    Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3′-5′ exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
Immunogen:    Synthetic peptide of human EXD2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 221992(EXD2 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 221992(Anti-EXD2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 221992(Anti-EXD2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D263846(Anti-EXD2 Antibody) at dilution 1/20.
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