Email: info@neweastbio.com   |  Call: 6109452007

FGR Rabbit pAb

Anti-FGR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222036

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222036
Product Name:   Anti-FGR Rabbit Polyclonal Antibody
Synonyms:   SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr
UNIPROT ID:   P09769 (Gene Accession – NP_005239 )
Background:    This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen:    Synthetic peptide of human FGR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 222036(FGR Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 222036(Anti-FGR Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 222036(Anti-FGR Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D263914(Anti-FGR Antibody) at dilution 1/70.
          Publications