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MRGPRD Rabbit pAb

Anti-MRGPRD Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222127

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222127
Product Name:   Anti-MRGPRD Rabbit Polyclonal Antibody
Synonyms:   MRGD; TGR7
UNIPROT ID:   Q8TDS7 (Gene Accession – NP_944605 )
Background:    May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca2+ influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Immunogen:    Synthetic peptide of human MRGPRD
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 222127(MRGPRD Antibody) at a dilution of 1/25(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 222127(Anti-MRGPRD Antibody) at dilution 1/25.
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