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HTRA4 Rabbit pAb

Anti-HTRA4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222208

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222208
Product Name:   Anti-HTRA4 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   P83105 (Gene Accession – NP_710159 )
Background:    This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Immunogen:    Synthetic peptide of human HTRA4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 222208(HTRA4 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the synthetic peptide and then with 222208(Anti-HTRA4 Antibody) at dilution 1/25.
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