Email: info@neweastbio.com   |  Call: 6109452007

XRCC1 Rabbit pAb

Anti-XRCC1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222345

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222345
Product Name:   Anti-XRCC1 Rabbit Polyclonal Antibody
Synonyms:   RCC; SCAR26
UNIPROT ID:   P18887 (Gene Accession – NP_006288 )
Background:    The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Immunogen:    Synthetic peptide of human XRCC1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 222345(XRCC1 Antibody) at a dilution of 1/75(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 222345(Anti-XRCC1 Antibody) at dilution 1/75.
          Publications