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DOK7 Rabbit pAb

Anti-DOK7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222408

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222408
Product Name:   Anti-DOK7 Rabbit Polyclonal Antibody
Synonyms:   CMS10; CMS1B; FADS3; C4orf25
UNIPROT ID:   Q18PE1 (Gene Accession – NP_775931 )
Background:    The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human DOK7
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 222408(DOK7 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 222408(Anti-DOK7 Antibody) at dilution 1/50.
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