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Neuropilin 1 Rabbit pAb

Anti-Neuropilin 1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225068

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225068
Product Name:   Anti-Neuropilin 1 Rabbit pAb
Synonyms:   NRP1; NRP; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; CD antigen CD304
UNIPROT ID:   O14786
Background:    The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
Immunogen:    The antiserum was produced against synthesized peptide derived from the Internal region of human NRP1. AA range:321-370
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 103 kDa; Observed MW: 100 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human kidney using Neuropilin 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Neuropilin 1 in 293 lysates using Neuropilin 1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human kidney using Neuropilin 1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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