NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225101 | ||
Product Name: Anti-B4GALT5 Rabbit pAb | ||
Synonyms: B4GALT5; Beta-1; 4-galactosyltransferase 5; Beta-1; 4-GalTase 5; Beta4Gal-T5; b4Gal-T5; Beta-1; 4-GalT II; UDP-Gal:beta-GlcNAc beta-1; 4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1; 4-galactosyltransferase 5 | ||
UNIPROT ID: O43286 | ||
Background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2. | ||
Immunogen: The antiserum was produced against synthesized peptide derived from human B4GALT5. AA range:321-370 | ||
Applications: WB,ELISA | ||
Recommended Dilutions: WB: 1/500-1/1000 ELISA: 1/10000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Clone ID: – | ||
MW: Calculated MW: 45 kDa; Observed MW: 40 kDa | ||
Isotype: IgG | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Mouse | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Tags & Cell Markers | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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