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IDO 2 Rabbit pAb

Anti-IDO 2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225189

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225189
Product Name:   Anti-IDO 2 Rabbit pAb
Synonyms:   IDO2; INDOL1; Indoleamine 2; 3-dioxygenase 2; IDO-2; Indoleamine 2; 3-dioxygenase-like protein 1; Indoleamine-pyrrole 2; 3-dioxygenase-like protein 1
UNIPROT ID:   Q6ZQW0
Background:    INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small inTine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
Immunogen:    The antiserum was produced against synthesized peptide derived from the Internal region of human IDO2. AA range:101-150
Applications:    WB,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 47 kDa; Observed MW: 47 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of IDO 2 in HeLa, HepG2 lysates using IDO 2 antibody.
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