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4E BP1 Rabbit pAb

Anti-4E BP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225260

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225260
Product Name:   Anti-4E BP1 Rabbit pAb
Synonyms:   EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
UNIPROT ID:   Q13541
Background:    Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.
Immunogen:    Synthetic peptide.
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 13 kDa; Observed MW: 15-20 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunoprecipitation analysis of 4E BP1 in Hela lysates using 4EBP1 antibody.

Western blot analysis of 4EBP1 in SH-SY5Y, C2C12 and 3T3 lysates using 4EBP1 antibody.

Western blot analysis of 4E BP1 in Jurkat, Hela and C6 lysates using 4EBP1 antibody.

Western blot analysis of 4E BP1 in C2C12, A549 and 3T3 lysates using 4E BP1 antibody
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