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IGF1 Receptor Rabbit pAb

Anti-IGF1 Receptor Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225286

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225286
Product Name:   Anti-IGF1 Receptor Rabbit pAb
Synonyms:   IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
UNIPROT ID:   P08069
Background:    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Immunogen:    Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
Applications:    WB,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 155 kDa; Observed MW: 95,200 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of IGF1 Receptor in MCF using IGF1 Receptor antibody.

Western blot analysis of IGF1 Receptor in 293 lysates usingIGF1 Receptor antibody. and the same antibody. preincubated with blocking peptide.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using IGF1 Receptor antibody(left) or the same antibody preincubated with blocking peptide (right).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications