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Phospho-PTEN (Ser380) Rabbit pAb

Anti-Phospho-PTEN (Ser380) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225288

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225288
Product Name:   Anti-Phospho-PTEN (Ser380) Rabbit pAb
Synonyms:   PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog
UNIPROT ID:   P60484
Background:    Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
Immunogen:    Synthetic peptide of human PTEN
Applications:    IHC-P,ICC/IF
Recommended Dilutions:    IHC: 1/50-1/100 ICC: 1/100-1/200
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:   
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of Phospho-PTEN (Ser380) in Hela cells using PTEN (Phospho-Ser380) antibody,and DAPI (blue).

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-PTEN (Ser380) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right.
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