Email: info@neweastbio.com   |  Call: 6109452007

ABCG2 Rabbit pAb

Anti-ABCG2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225341

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225341
Product Name:   Anti-ABCG2 Rabbit pAb
Synonyms:   ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD338
UNIPROT ID:   Q9UNQ0
Background:    ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Immunogen:    The antiserum was produced against synthesized peptide derived from human ABCG2. AA range:289-338
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 72 kDa; Observed MW: 72 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of ABCG2 in HT-29 lysates using ABCG2 antibody

Western blot analysis of ABCG2 in various lysates using ABCG2 antibody.

Western blot analysis of ABCG2 in various lysates using ABCG2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human brain using ABCG2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right.
          Publications