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TAK1 Rabbit pAb

Anti-TAK1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225407

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225407
Product Name:   Anti-TAK1 Rabbit pAb
Synonyms:   MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
UNIPROT ID:   O43318
Background:    Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
Immunogen:    The antiserum was produced against synthesized peptide derived from human MAP3K7. AA range:161-210
Applications:    ICC/IF,WB,IHC-F,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 67 kDa; Observed MW: 70 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using TAK1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of TAK1 in Jurkat lysates, treated with heat shock lysates using TAK1 antibody. The lane on the right is blocked with the synthesized peptide.

Immunofluorescence analysis of TAK1 in rat kidney using Tak1 antibody(red),and DAPI (blue).

Immunofluorescence analysis of TAK1 in mouse kidney using Tak1 antibody(red),and DAPI (blue).
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