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Fibrillarin Rabbit pAb

Anti-Fibrillarin Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225639

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225639
Product Name:   Anti-Fibrillarin Rabbit pAb
Synonyms:   FIB; FLRN; Nop1; RNU3IP1
UNIPROT ID:   P22087
Background:    Fibrillarin is a 2′-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2′-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
Immunogen:    A synthesized peptide derived from human Fibrillarin
Applications:    WB,IHC-P,ICC/IF,IP,FC
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 34 kDa; Observed MW: 34 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Tags & Cell Markers
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human testis using Fibrillarin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Fibrillarin in HepG2 lysates using Fibrillarin antibody.

Immunofluorescence analysis of Fibrillarin in Hela using Fibrillarin antibody.
          Publications