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KMT6 Rabbit pAb

Anti-KMT6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225750

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225750
Product Name:   Anti-KMT6 Rabbit pAb
Synonyms:   WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2
UNIPROT ID:   Q15910
Background:    Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates ‘Lys-9’ and ‘Lys-27’ of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate ‘Lys-27’ of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Immunogen:    A synthesized peptide derived from human KMT6 / EZH2
Applications:    WB,IHC-P,ICC/IF,FC
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 85 kDa; Observed MW: 98 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using KMT6 / EZH2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of KMT6 / EZH2 in HEK293 lysates using KMT6 antibody.

Immunofluorescence analysis of KMT6 in Hela using KMT6 / EZH2 antibody.
          Publications