NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261482 |
Product Name: Anti-Cardiac Troponin I (2D10) Mouse Monoclonal Antibody |
Synonyms: TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I |
UNIPROT ID: P19429 |
Background: Troponin I (TnI) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle; see also TNNI1 (MIM 191042). The others are troponin T (TnT; see MIM 191041) and troponin C (TnC; see MIM 191040). |
Immunogen: Synthetic peptides corresponding to the sequence of human Cardiac Troponin I. |
Applications: WB,ELISA |
Recommended Dilutions: WB: 1/500-1/1000 ELISA: 1/10000 |
Host Species: Mouse |
Clonality: Mouse Monoclonal |
Clone ID: 2D10-C5 |
MW: Calculated MW: 24 kDa; Observed MW: 28 kDa |
Isotype: IgG2a |
Purification: Affinity Purified |
Species Reactivity: Human,Mouse,Rat |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Signal Transduction |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of Cardiac Troponin I (2D10) in rat and mouse heart lysates using Troponin I (2012952D10) antibody. |