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CRTC3 Rabbit mAb

Anti-CRTC3 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261630

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261630
Product Name:   Anti-CRTC3 Rabbit Monoclonal Antibody
Synonyms:   TORC3; FLJ21868; CRTC3
UNIPROT ID:   Q6UUV7
Background:    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ‘Ser-133’ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small inTine, spleen and stomach.
Immunogen:    A synthetic peptide of human CRTC3
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-4C9
MW:    Calculated MW: 67 kDa; Observed MW: 78 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Microbiology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of CRTC3 in K562, rat Brain, C6, 3T3, Hela lysates using CRTC3 antibody.

Immunocytochemistry analysis of CRTC3 (green) in Hela using CRTC3 antibody,and DAPI(blue).
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