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APPL Rabbit mAb

Anti-APPL Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261861

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261861
Product Name:   Anti-APPL Rabbit Monoclonal Antibody
Synonyms:   APPL1; APPL; DIP13A; KIAA1428; DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1
UNIPROT ID:   Q9UKG1
Background:    Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
Immunogen:    A synthetic peptide of human APPL
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-8D5
MW:    Calculated MW: 80 kDa; Observed MW: 80 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using APPL antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of APPL in rat Brain, C6, 3T3, Hela lysates using APPL antibody.
          Publications