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Integrin alpha 5 Rabbit mAb

Anti-Integrin alpha 5 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262414

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262414
Product Name:   Anti-Integrin alpha 5 Rabbit Monoclonal Antibody
Synonyms:   ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e
UNIPROT ID:   P08648
Background:    Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
Immunogen:    A synthetic peptide of human Integrin alpha 5
Applications:    WB,IHC-P,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R02-3G4
MW:    Calculated MW: 115 kDa; Observed MW: 150 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Integrin alpha 5 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Integrin alpha 5 in K562, 3T3 lysates using Integrin alpha 5 antibody.
          Publications