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KDM4B Rabbit mAb

Anti-KDM4B Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262445

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262445
Product Name:   Anti-KDM4B Rabbit Monoclonal Antibody
Synonyms:   KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
UNIPROT ID:   O94953
Background:    Histone demethylase that specifically demethylates ‘Lys-9’ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ‘Lys-4’, H3 ‘Lys-27’, H3 ‘Lys-36’ nor H4 ‘Lys-20’. Only able to demethylate trimethylated H3 ‘Lys-9’, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Immunogen:    A synthetic peptide of human KDM4B/JMJD2B
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-9G9
MW:    Calculated MW: 122 kDa; Observed MW: 150 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KDM4B/JMJD2B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of KDM4B in 293, COS7 lysates using KDM4B antibody.

Immunocytochemistry analysis of KDM4B/JMJD2B(green) in Hela using KDM4B/JMJD2B antibody,and DAPI(blue)
          Publications