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MEF2A Rabbit mAb

Anti-MEF2A Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262503

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262503
Product Name:   Anti-MEF2A Rabbit Monoclonal Antibody
Synonyms:   mef2; ADCAD1; RSRFC4; RSRFC9
UNIPROT ID:   Q02078
Background:    Transcriptional activator which binds specifically to the MEF2 element, 5′-YTA[AT]4TAR-3′, found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Immunogen:    A synthetic peptide of human MEF2A
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-9A6
MW:    Calculated MW: 55 kDa; Observed MW: 55 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of MEF2A in 293T, Jurkat lysates using MEF2A antibody.

Western blot analysis of MEF2A in mouse brain, rat brain lysates using MEF2A antibody.
          Publications