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MMP12 Rabbit mAb

Anti-MMP12 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262526

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262526
Product Name:   Anti-MMP12 Rabbit Monoclonal Antibody
Synonyms:   Macrophage metalloelastase; MME; 3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME
UNIPROT ID:   P39900
Background:    MMP-12 lacks a transmembrane domain and furin cleavage site. The zymogen for MMP-12 is about 54 kDa, and is quickly activated to the 45 kDa form, and this breaks down to cascade of active forms, ending with the common 22 kDa form.Stimulated macrophages produce MMP-12; it has also been found in osteosarcoma cells, synovial fibroblasts and lung fibroblasts.
Immunogen:    A synthetic peptide of human MMP12
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-2B9
MW:    Calculated MW: 54 kDa; Observed MW: 54,45 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat,Hamster
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of MMP12 in CHO-K1, C6 lysates using MMP12 antibody.

Western blot analysis of MMP12 in Hela lysates using MMP12 antibody.
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