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PLK1 Rabbit mAb

Anti-PLK1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262735

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262735
Product Name:   Anti-PLK1 Rabbit Monoclonal Antibody
Synonyms:   PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13
UNIPROT ID:   P53350
Background:    Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.
Immunogen:    A synthetic peptide of human PLK1
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-3E0
MW:    Calculated MW: 68 kDa; Observed MW: 68 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of PLK1 (green) in Hela using PLK1 antibody,and DAPI(blue)

Western blot analysis of PLK1 in Jurkat, C6 lysates using PLK1 antibody.
          Publications