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MLH1 Rabbit mAb

Anti-MLH1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263429

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263429
Product Name:   Anti-MLH1 Rabbit Monoclonal Antibody
Synonyms:   MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
UNIPROT ID:   P40692
Background:    This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Immunogen:    Recombinant protein of human MLH1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-5D3
MW:    Calculated MW: 85 kDa; Observed MW: 85 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of MLH1 (green) in hela using MLH1 antibody,and DAPI(blue)

Western blot analysis of MLH1 in Hela, A549, HL-60, U2OS lysates using MLH1 antibody.
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