NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
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β-Actin Polyclonal Antibody
Cat. #: 21011 |
Gene Symbol: ACTB |
Description: Anti-β-actin Rabbit Polyclonal Antibody |
Background: Actin is expressed in all eukaryotic cells and is the major component of the cytoskeleton. At least six types of actin are present in mammalian tissues and fall into three classes. β-actin expression is limited to various types of muscle and it regulates contactile potentials for the muscle cells, whereas β and γ actins, also known as cytoplasmic actins, are predominantly expressed in nonmuscle cells, controlling cell structure and motility. |
Immunogen: Synthetic peptide from the N-terminal of β-actin |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:100-1:2000 IHC 1:50-1:100 |
Concentration: 0.2 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-β actin antibody recognizes β-actin of vertebrates and invertebrates |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: HEK-293T whole-cell lysate was used for western blot with Anti-β actin polyclonal antibody (cat # 21011). |