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AANAT Rabbit pAb

Anti-AANAT Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217177

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217177
Product Name:   Anti-AANAT Rabbit Polyclonal Antibody
Synonyms:   DSPS; SNAT
UNIPROT ID:   Q16613 (Gene Accession – BC069434 )
Background:    The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human AANAT
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217177(AANAT Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217177(Anti-AANAT Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 217177(Anti-AANAT Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D221925(Anti-AANAT Antibody) at dilution 1/40.
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