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ABCC1 Rabbit pAb

Anti-ABCC1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221182

   Size:   100 μl

In Stock

            Product Description          
Cat.#:   S221182
Product Name:   Anti-ABCC1 Rabbit Polyclonal Antibody
Synonyms:   MRP; ABCC; GS-X; MRP1; ABC29
UNIPROT ID:   P33527 (Gene Accession – NP_004987 )
Background:    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates.
Immunogen:    Synthetic peptide of human ABCC1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221182(ABCC1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221182(Anti-ABCC1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 221182(Anti-ABCC1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D262671(Anti-ABCC1 Antibody) at dilution 1/25.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: A431 cell;
Primary antibody: 221182(ABCC1 Antibody) at dilution 1/350;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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