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ABCC3 Rabbit pAb

Anti-ABCC3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219917

   Size:   100 μl

In Stock

            Product Description          
Cat.#:   S219917
Product Name:   Anti-ABCC3 Rabbit Polyclonal Antibody
Synonyms:   MLP2, MRP3, ABC31, MOAT-D, cMOAT2, EST90757
UNIPROT ID:   O15438 (Gene Accession – NP_003777 )
Background:    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [
Immunogen:    Synthetic peptide of human ABCC3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219917(ABCC3 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219917(Anti-ABCC3 Antibody) at dilution 1/20.
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