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ACD Rabbit pAb

Anti-ACD Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215600

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215600
Product Name:   Anti-ACD Rabbit Polyclonal Antibody
Synonyms:   PIP1; PTOP; TPP1; TINT1
UNIPROT ID:   Q96AP0 (Gene Accession – NP_001075955 )
Background:    This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric comple,x which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this comple,x and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
Immunogen:    Synthetic peptide of human ACD
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 215600(ACD Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 215600(Anti-ACD Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 215600(Anti-ACD Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D163606(Anti-ACD Antibody) at dilution 1/20.
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