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ACTN2 Rabbit pAb

Anti-ACTN2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220877

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220877
Product Name:   Anti-ACTN2 Rabbit Polyclonal Antibody
Synonyms:   MPD6; CMH23; CMD1AA; MYOCOZ
UNIPROT ID:   P35609 (Gene Accession – NP_001094 )
Background:    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human ACTN2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human skeletal muscle tissue using 220877(ACTN2 Antibody) at a dilution of 1/50(Cytoplasm).

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart and muscle tissue;
Primary antibody: 220877(ACTN2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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