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ACVR1B Rabbit pAb

Anti-ACVR1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216234

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216234
Product Name:   Anti-ACVR1B Rabbit Polyclonal Antibody
Synonyms:   ALK4; SKR2; ACTRIB; ACVRLK4
UNIPROT ID:   P36896 (Gene Accession – BC000254 )
Background:    This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human ACVR1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 216234(ACVR1B Antibody) at a dilution of 1/25(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 216234(Anti-ACVR1B Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216234(Anti-ACVR1B Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D220045(Anti-ACVR1B Antibody) at dilution 1/25.
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