Email: info@neweastbio.com   |  Call: 6109452007

ACVR1C Rabbit pAb

Anti-ACVR1C Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216924

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216924
Product Name:   Anti-ACVR1C Rabbit Polyclonal Antibody
Synonyms:   ALK7; ACVRLK7
UNIPROT ID:   Q8NER5 (Gene Accession – BC022530 )
Background:    ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
Immunogen:    Fusion protein of human ACVR1C
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 216924(ACVR1C Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 216924(Anti-ACVR1C Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216924(Anti-ACVR1C Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D221481(Anti-ACVR1C Antibody) at dilution 1/15.
          Publications