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ACVRL1 Rabbit pAb

Anti-ACVRL1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221203

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221203
Product Name:   Anti-ACVRL1 Rabbit Polyclonal Antibody
Synonyms:   HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
UNIPROT ID:   P37023 (Gene Accession – NP_000011 )
Background:    This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases.
Immunogen:    Synthetic peptide of human ACVRL1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221203(ACVRL1 Antibody) at a dilution of 1/30(Cytoplasm or Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221203(Anti-ACVRL1 Antibody) at dilution 1/30.
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