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ADAMTS3 Rabbit pAb

Anti-ADAMTS3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221303

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221303
Product Name:   Anti-ADAMTS3 Rabbit Polyclonal Antibody
Synonyms:   HKLLS3; ADAMTS-4
UNIPROT ID:   O15072 (Gene Accession – NP_055058 )
Background:    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
Immunogen:    Synthetic peptide of human ADAMTS3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221303(ADAMTS3 Antibody) at a dilution of 1/55(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221303(Anti-ADAMTS3 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 221303(Anti-ADAMTS3 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D262832(Anti-ADAMTS3 Antibody) at dilution 1/55.
          Publications