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ADAMTSL2 Rabbit pAb

Anti-ADAMTSL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216942

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216942
Product Name:   Anti-ADAMTSL2 Rabbit Polyclonal Antibody
Synonyms:   GPHYSD1; ADAMTSL-2
UNIPROT ID:   Q86TH1 (Gene Accession – BC050544 )
Background:    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
Immunogen:    Fusion protein of human ADAMTSL2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216942(ADAMTSL2 Antibody) at a dilution of 1/70(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216942(Anti-ADAMTSL2 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 216942(Anti-ADAMTSL2 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D221513(Anti-ADAMTSL2 Antibody) at dilution 1/70.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: A549 cell lysate;
Primary antibody: 216942(ADAMTSL2 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 3 seconds
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