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ADCY5/6 Rabbit pAb

Anti-ADCY5/6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225427

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225427
Product Name:   Anti-ADCY5/6 Rabbit pAb
Synonyms:   ADCY5; Adenylate cyclase type 5; ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5; ADCY6; KIAA0422; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitabl
UNIPROT ID:   O95622/O43306
Background:    ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.
Immunogen:    The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
Applications:    WB,IHC-F,IHC-P,ICC/IF,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 139 kDa; Observed MW: 139 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of ADCY5/6 in COLO25 lysates using ADCY5/6 antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of ADCY5/6 in various lysates using ADCY5/6 antibody.

Western blot analysis of ADCY5/6 in COLO205 lysates using A Cyclase V/VI antibody.

Western blot analysis of ADCY5/6 in HUVEC lysates using ADCY5/6 antibody.
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