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ADCY5 Rabbit pAb

Anti-ADCY5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220269

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220269
Product Name:   Anti-ADCY5 Rabbit Polyclonal Antibody
Synonyms:   AC5; FDFM
UNIPROT ID:   O95622 (Gene Accession – NP_001186571 )
Background:    This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
Immunogen:    Synthetic peptide of human ADCY5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220269(ADCY5 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220269(Anti-ADCY5 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220269(Anti-ADCY5 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D261242(Anti-ADCY5 Antibody) at dilution 1/40.
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