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ADRM1 Rabbit mAb

Anti-ADRM1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261804

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261804
Product Name:   Anti-ADRM1 Rabbit Monoclonal Antibody
Synonyms:   ARM1; ARM-1; GP110
UNIPROT ID:   Q16186
Background:    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
Immunogen:    A synthetic peptide of human ADRM1
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-2A8
MW:    Calculated MW: 42 kDa; Observed MW: 42 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of ADRM1(green) in Hela using ADRM1 antibody,and DAPI(blue)

Western blot analysis of ADRM1 in K562, Hela lysates using ADRM1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using ADRM1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications