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ADSL Rabbit pAb

Anti-ADSL Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216949

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216949
Product Name:   Anti-ADSL Rabbit Polyclonal Antibody
Synonyms:   ASL; AMPS; ASASE
UNIPROT ID:   P30566 (Gene Accession – BC000253 )
Background:    Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human ADSL
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216949(ADSL Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216949(Anti-ADSL Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216949(Anti-ADSL Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D221520(Anti-ADSL Antibody) at dilution 1/20.
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