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AF10 Rabbit mAb

Anti-AF10 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261807

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261807
Product Name:   Anti-AF10 Rabbit Monoclonal Antibody
Synonyms:   MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein
UNIPROT ID:   P55197
Background:    Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 ‘Lys-79’ dimethylation (H3K79me2) and gene activation (PubMed:26439302).
Immunogen:    Recombinant protein of human AF10
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-2G2
MW:    Calculated MW: 113 kDa; Observed MW: 140 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of AF10 in Hela, K562 lysates using AF10 antibody.
          Publications