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AGAP4 Rabbit pAb

Anti-AGAP4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221305

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221305
Product Name:   Anti-AGAP4 Rabbit Polyclonal Antibody
Synonyms:   AGAP8; MRIP2; AGAP-4; AGAP-8; CTGLF1; CTGLF5
UNIPROT ID:   Q96P64 (Gene Accession – NP_001263272 )
Background:    AGAP4(also known as Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4) is a GTPase activating protein. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. AGAP4 and other AGAP proteins likely function in the secretory pathway, which could explain a link with the invasive behavior of cancer cells. Reliable antibodies would be invaluable for studies of the physiologic function of the proteins and how is may be linked to cancer cell invasive behavior.
Immunogen:    Synthetic peptide of human AGAP4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221305(AGAP4 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221305(Anti-AGAP4 Antibody) at dilution 1/40.
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