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AKR1B1 Rabbit pAb

Anti-AKR1B1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220044

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220044
Product Name:   Anti-AKR1B1 Rabbit Polyclonal Antibody
Synonyms:   AR; ADR; ALR2; ALDR1
UNIPROT ID:   P15121 (Gene Accession – NP_001619 )
Background:    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
Immunogen:    Synthetic peptide of human AKR1B1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220044(AKR1B1 Antibody) at a dilution of 1/30(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220044(Anti-AKR1B1 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 220044(Anti-AKR1B1 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D260849(Anti-AKR1B1 Antibody) at dilution 1/30.

Gel: 10%SDS-PAGE, Lysate: 27 μg;
Lane: Hela cells;
Primary antibody: 220044(AKR1B1 Antibody) at dilution 1/550;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 second
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