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ALDH1A1/ALDH1A2/ALDH1A3 Rabbit pAb

Anti-ALDH1A1/ALDH1A2/ALDH1A3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216241

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216241
Product Name:   Anti-ALDH1A1/ALDH1A2/ALDH1A3 Rabbit Polyclonal Antibody
Synonyms:   ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1; RALDH2, RALDH2-T, RALDH(II); ALDH6, RALDH3, ALDH1A6
UNIPROT ID:   P00352/O94788/P47895 (Gene Accession – BC001505/BC030589/BC069274 )
Background:    This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
Immunogen:    Fusion protein of human ALDH1A1/ALDH1A2/ALDH1A3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-150;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Neuroscience, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216241(ALDH1A1/ALDH1A2/ALDH1A3 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216241(Anti-ALDH1A1/ALDH1A2/ALDH1A3 Antibody) at dilution 1/40.

Gel: 10%SDS-PAGE, Lysate: 30 μg;
Lane: Mouse liver tissue;
Primary antibody: 216241(ALDH1A1/ALDH1A2/ALDH1A3 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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