NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S216241 | ||||
Product Name: Anti-ALDH1A1/ALDH1A2/ALDH1A3 Rabbit Polyclonal Antibody | ||||
Synonyms: ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1; RALDH2, RALDH2-T, RALDH(II); ALDH6, RALDH3, ALDH1A6 | ||||
UNIPROT ID: P00352/O94788/P47895 (Gene Accession – BC001505/BC030589/BC069274 ) | ||||
Background: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. | ||||
Immunogen: Fusion protein of human ALDH1A1/ALDH1A2/ALDH1A3 | ||||
Applications: ELISA, WB, IHC | ||||
Recommended Dilutions: IHC: 50-150;WB: 500-2000;ELISA: 1000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Cancer, Neuroscience, Stem Cells | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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