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ALDH3A1 Rabbit pAb

Anti-ALDH3A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216971

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216971
Product Name:   Anti-ALDH3A1 Rabbit Polyclonal Antibody
Synonyms:   ALDH3; ALDHIII
UNIPROT ID:   P30838 (Gene Accession – BC004370 )
Background:    Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen:    Fusion protein of human ALDH3A1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 216971(ALDH3A1 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the fusion protein and then with 216971(Anti-ALDH3A1 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216971(Anti-ALDH3A1 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D221567(Anti-ALDH3A1 Antibody) at dilution 1/55.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: A549 cells, mouse eye tissue;
Primary antibody: 216971(ALDH3A1 Antibody) at dilution 1/750;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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