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ALDH5A1 Rabbit pAb

Anti-ALDH5A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220282

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220282
Product Name:   Anti-ALDH5A1 Rabbit Polyclonal Antibody
Synonyms:   SSDH; SSADH
UNIPROT ID:   P51649 (Gene Accession – NP_001071 )
Background:    This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Immunogen:    Synthetic peptide of human ALDH5A1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220282(ALDH5A1 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220282(Anti-ALDH5A1 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 220282(Anti-ALDH5A1 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D261257(Anti-ALDH5A1 Antibody) at dilution 1/35.
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